On the GO! fabric cutters, you can cut up to six layers of 100% cotton fabric at a time. On the Studio 2 Fabric Cutter, you can cut up to ten layers. The number of layers you are able to cut with other types of fabric depends on the thickness and density of the fabric plus the intricacy of the die design. We recommend trying some test cuts to determine how many layers work best with each type of fabric and die combination.